Efficacy of PCSO-524® and prednisolone combination treatment for neck pain in Chihuahua dog with Chiari-like malformation and syringomyelia

Antinol® Cases Study 2017 Content

2nd Winning Award

Efficacy of PCSO-524® and prednisolone combination treatment for neck pain in Chihuahua dog with Chiari-like malformation and syringomyelia

Pichanun Linharatanaruksa, DVM, PhD

VET KU Research Support Center, Faculty of Veterinary Medicine, Kasetsart University

Abstract

A 18-month-old male intact chihuahua presented with recurrent neck pain within 3 months after stop using prednisolone.

Upon physical and neurological examination, dog displayed pain and neck stiffness without neurological deficits. Radiographic findings of cervical spine was normal.

The dog was treated with prednisolone to relieve pain and inflammation and showed improvement of clinical signs. However, the recurrence occurred in 7 months with more severity. Magnetic resonance

imaging (MRI) demonstrated Chiari-like malformation and syringomyelia at C2-C4 and C7-T1 region.

PCSO-524® (VetzPetz Antinol®) was administered in combination with prednisolone and gabapentin. The clinical signs improved in 2 weeks so prednisolone was gradually reduced until discontinued but dose of PCSO-524® remained constantly. The dog was able to recover from neck pain and continued life activities as normal.

Long-term supplement of PCSO-524® (VetzPetz Antinol®) was effective for reducing inflammation of spinal cord in dog suffered from neck pain caused by syringomyelia.