Use of PCSO-524® for Treatment of Spine Fracture in Conjunction with Pedicle Screw-Rod Fixation (PSRF)

Antinol® Cases Study 2017 Content

2nd Winning Award

Use of PCSO-524® for Treatment of Spine Fracture in Conjunction with Pedicle Screw-Rod Fixation (PSRF)

Titiphan Trakanpol, DVM Small Animal Hospital, Chulalongkorn University

Abstract

An intact male mixed breed dog aged 2 years engaged in a fight with several dogs resulting in disable of hind limbs and loss control of elimination. Physical and radiographic examination showed fracture and luxation of the 7th lumbar vertebrae. Spinal cord injury (SCI) was also found and the fracture was identified as the cause. The spinal cord trauma could occur since the incident and was left for more than 2 weeks.

Pedicle screw-rod fixation (PSRF) was operated to fix the vertebral column. After the second operation, it was suspected that there was remain of inflammatory cytokines that probably increased after the operation. Anti-inflammatory medication for prohibition of inflammatory cytokines synthesis was essential but its adverse effect must be concerned. The study therefore used holistic treatment including PSRF, non-steroidal drug and PCSO-524® anti-inflammatory extract, in conjunction with physical therapy.

Follow-up examination on neurological system, walking, and urinary system showed promising result. The neurological system was restored, and adverse effect of long-term use had not been found.

Keywords: PCSO-524®, lumbosacral fracture-luxation, pedicle screw-rod fixation (PSRF), spinal cord injury (SCI), postoperative care