The Effectiveness of Marine Based Fatty Acid Compound and NSAIDs for the Treatment of Canine Osteoarthritis: a preliminary study

Abstract

Introduction: The Objectives of this study were to investigate the effectiveness of PCSO-524, NSAIDs and combination of NSAIDs and PCSO-524 in the treatment of canine osteoarthritis through the use of force plate gait analysis. 

Study Design:  A prospective block-randomized single-blinded study. 

Animals: Thirty client-owned dogs that had clinical and radiographic evidences of hip or stifle osteoarthritis.

Discussion/Conclusion: 

Force plate gait analysis is a gold standard for evaluation of lameness because it has 93% sensitivity and 94% specificity. It may detect changes in the levels of subclinical lameness that cannot be detected by human eye. Even though increased PVF were demonstrated in all treatment groups, the highest change was demonstrated in the group to which a combination of NSAIDs and PCSO-524 was administered. This may imply that there are beneficial effects of PCSO-524 in combination with NSAIDs. Long- term aggregated data of the result of a higher dosage should be explored further.

*Corresponding author. E-mail address: mvijarnsorn@gmail.com