Use of PCSO-524® (Antinol)® for treatment of Obsessive-Compulsive Disorders (OCD) in Domestic Short Hair Cat

Antinol® Cases Study 2017 Content

1st Winning Award

Use of PCSO-524® (Antinol)® for treatment of Obsessive-Compulsive Disorders (OCD) in Domestic Short Hair Cat

Kanok Bamrungsri, DVM Chaengwatthana Animal Hospital

Abstract

A 3 years old domestic short hair cat had shown behavioral disorder after castration 4 months ago.

Failure to control pain and inflammation after the operation could induce maladaptive pain and misbehavior. The cat had decreased water and diet consumption, failed to urinate in designated area, rubbed his face with surrounding objects, started destructive chewing, and showed sign of depression, anxiety, aggression, excessive grooming and scratching. Inflamed skin was observed at head, neck, back and legs with skin flaking especially at the medial right hind limb where a bruise was also found.

The clinical signs were consistent with obsessive-compulsive disorders (OCD).

Pathological examination found edema of epidermis andinfiltration of mature mast cells in hair follicle. Treatment with PCSO-524® (Antinol)® for 180 days had shown that the misbehavior was improved due to decreased pain and skin inflammation. Healthier coat and skin appearance was noticed after 30 consecutive days of PCSO-524® (Antinol®) intake. Pathological follow-up showed less inflammation of epidermis and decreased mast cells infiltration.

It was shown that PCSO-524® (Antinol®) could reduce pain and inflammation that caused anxiety and consequently OCD in cats. Additional effects included antihistamine, antiallergy, and skin neurishing.

The extract is appropriate for long-term use as it has been shown that 180 days intake was effective without causing abnormality of hematology and blood chemistry indicators such as ALT, creatinine, and BUN. In this case we found that OCD had re-emerged after termination of PCSO-524® (Antinol®) or replacing the supplement with other neutraceuticalsubstance such as Krill oil 425 mg.

Keywords: Cat, PCSO-524® (Antinol®), obsessive-compulsive disorders (OCD)