Effects of PCSO-524® (Antinol®) Supplementation during 12 Months Follow-up in 2 Cats with Cystitis and Chronic Renal Disease

Antinol® Cases Study 2016 Content

3rd Winning Award

Effects of PCSO-524® (Antinol®) Supplementation during 12 Months Follow-up in 2 Cats with Cystitis and Chronic Renal Disease

Roungrut Puttirongkawat, DVM, PhD

Faculty of Veterinary Science, Mahidol University

Abstract

Two female cats, spayed, lived in the same house, aged 17 years weighted 2.2 kg and 10 years 4.4 kg, were having chronic renal failure and concurrent cystitis.

Senility was suspected etiologyof chronic renal failure in the first cat. However, cystitis occurred by an unknown cause. Clinical signs of cystitis included urinary retention, polyuria but low urine output, and hematuria. Chronic renal failure in the second cat was caused by hydronephrosis of both kidneys and bladder stone which was identified by hypoechoic of urinary bladder. The second cat did not show any clinical signs of lower urinary tract. Both cats showed signs of uremic syndrome; polydipsia, polyuria, anorexia, weight loss, coarse hair, depression, halitosis, and vomiting.

Both cats were treated with fluid therapy intravenously in the early period and later subcutaneously. The diet was changed to diet formulated for cats with renal failure (Hill’s Prescription diet k/d) for both cats. Avastamine (RenAvastTM) 1 capsule bid for 1 month, Cystaid® cat (Acetyl 0-Glucosamine: NAG125 mg) l capsule bid for 1 month, and PCSO-524® (Vetz Petz Antinol®) 1 capsule sid continuously were prescribed for the first cat. The second cat received only PCSO-524® (Vetz Petz Antinol®) 1 capsule sid continuously.

The treatment results showed general health improvement, weight gain (2.6 kg and 5.1 kg in the first and second cat, respectively), less hair loss, decreased degree of polydipsia and polyuria, and improvement of blood parameters. No adverse effect of the continuous treatment was found after 18 and 13 months in the first and second cat, respectively.

Keywords: Antinol®, PCS0-524®, chronic renal failure, cystitis, feline idiopathic cystitis, cat